Impact of Craniocerebral Hypothermia and Cryopreserved Cord Blood on Reproductive Function of Male Rats with Chronic Alcohol Intoxication-Reference-Cited by-同舟云学术

Impact of Craniocerebral Hypothermia and Cryopreserved Cord Blood on Reproductive Function of Male Rats with Chronic Alcohol Intoxication

Published:2020-12-17 Issue:4 Volume:30 Page:369-379
ISSN:2307-6143
Container-title:Problems of Cryobiology and Cryomedicine
language:
Short-container-title:Probl Cryobiol Cryomed

Author:

Lomakin Іvan, ,Kudokotseva Olga,Babiichuk Vladyslav,Kryshtal Yevhenii, , ,

Abstract

In this work, we have studied the impact of chronic alcohol intoxication (CAI) on reproductive function in male rats. Prolonged alcohol abuse has been shown to significantly reduce the manifestation rate of sexual activation and testosterone level in blood serum of male rats with CAI following exposure to a receptive female, as well as to change their seminal fl uid composition. The rhythmic craniocerebral hypothermia (rCCH), combined with the administration of cryopreserved cord blood leukoconcentrate (cCBL) ensured to a greater extent the dynamics of functional integrity recovery of the CAI-altered reproductive system in male rats, if compared to each of these methods used solely. The authors have hypothesized the rCCH and cCBL to activate the hypothalamicpituitary system, affecting thereby the testosterone synthesis and spermatogenesis stimulation.

Publisher

National Academy of Sciences of Ukraine (Co. LTD Ukrinformnauka)

Subject

Medicine (miscellaneous),Biophysics

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