Abstract
In this research, we have studied the mitotic activity of bone marrow when applying medicinal leeches and short-term hypothermia. The bone marrow mitotic indices were compared within an immediate examination of the thigh removed from the body and during a short-term hypothermia. As a result, no statistical differences were found between the mitotic levels during immediate examination and a short-term hypothermia in the intact animals and those after medicinal leech application, that evidenced to a hypothermal fixation of initial level of this index, preservation of biomembrane physiological state prior to hypotonic stress and cell morphology. The used here short-term hypothermia on bone marrow cells may be included in the multi-profile algorithm of laboratory analysis when studying a mitotic index in actively proliferating cells.
Publisher
National Academy of Sciences of Ukraine (Co. LTD Ukrinformnauka) (Publications)
Subject
Medicine (miscellaneous),Biophysics
Reference20 articles.
1. 1. Aminov R, Aminova A, Makyeyeva L. Morphological parameters of spleen and thymus of the male rats on the basis of the hirudological influence of Hirudo verbana. Ann Parasitol. 2022; 68(1): 55-60.
2. The effect of the biologically complex of a medical leech active substances on the immunosuppressive state of rats;Aminov;Jordan J Biol Sci,2022
3. 3. Aminov RF, Frolov AK. Influence of ectoparasite - Hirudo verbana on morphogenetic reactions of the host organism - rattus. Curr Trends Immunol. 2017; 18: 107-17.
4. 4. Aminov RF, Frolov AK. The impact of fetal load of Hirudo verbana saline extract antigens on morphometrical, hematological and immunological parameters of rats in the early stages of post-embryonic development. Ann Parasitol. 2018; 64(1): 13-20.
5. 5. Aminov RF, Frolov OK. [Proliferative activity of bone marrow cells of rats under the influence of biologically active substances of a medicinal leech]. Regulatory Mechanisms in Biosystems. 2017; 8(4): 501-5. Ukrainian.