Transformation of substituted 3-hydroxy-4-[(2E)-3-arylprop-2-enoyl]-1,5-dihydro-2H-pyrrol-2-ones by the action of I2/DMSO into derivatives 2-aryl-5,6-dihydropyrano[2,3-c]pyrrole-4,7-diones-Reference-Cited by-同舟云学术

Transformation of substituted 3-hydroxy-4-[(2E)-3-arylprop-2-enoyl]-1,5-dihydro-2H-pyrrol-2-ones by the action of I2/DMSO into derivatives 2-aryl-5,6-dihydropyrano[2,3-c]pyrrole-4,7-diones

Published:2021-12-30 Issue:2 Volume:16 Page:3-11
ISSN:1814-9766
Container-title:Ukrainica Bioorganica Acta
language:en
Short-container-title:Ukr. Bioorg. Acta

Author:

Vydzhak Roman¹^ORCID,Panchishin Svitlana¹^ORCID,Prostota Yaroslav¹^ORCID,Brovarets Volodymyr¹^ORCID

Affiliation:

1. V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the NAS of Ukraine

Abstract

The effective and simple synthetic preparative procedure for obtaining of various derivatives of 2-aryl-5,6-dihydropyrano[2,3-c]pyrrole-4,7-diones applying the I2/DMSO oxidation of 3-hydroxy-4-[(2E)-3-arylprop-2-enoyl]-1,5-dihydro-2H-pyrrol-2-ones was developed. This protocol was found to be compatible with a wide range of substituents and gave the reliable synthetic pathway for the obtaining of target compounds with a wide range of substituents under mild conditions. All obtained substances can be easily isolated and purified by crystallization without application of more complex and labour intensive purification methods

Publisher

National Academy of Sciences of Ukraine (Co. LTD Ukrinformnauka) (Publications)

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