Electrospray propelled by ionic wind in a bipolar system for direct delivery of charge reduced nanoparticles

Author:

Dau Van T.,Vu Trung-HieuORCID,Tran Canh-Dung,Nguyen Thanh Viet,Nguyen Tuan-Khoa,Dinh Toan,Phan Hoang-Phuong,Shimizu Kazunori,Nguyen Nam-Trung,Dao Dzung V.

Abstract

Abstract We present a conceptual design to generate and deliver nanoparticles in one unique system based on electrohydrodynamic atomisation (EHDA) without the restriction of the collector. The present EHDA bipolar configuration consists of a capillary nozzle and a pin, both act as emitters and as the reference electrodes of each other. Under an applied voltage, the capillary nozzle sprays droplets while the pin generates ion wind via corona discharge. During spraying process, droplets’ charge is significantly reduced by interacting with counter ions and propelled away from the electrodes by the momentum of ion winds accumulated from corona discharge. Thus, the present technique can yield promising applications in effective respiratory delivery of nanomedicine.

Publisher

IOP Publishing

Subject

General Physics and Astronomy,General Engineering

Cited by 11 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Generation of airborne particles toward inhalation drug delivery via electro-neutralization electrospray;2024 IEEE 19th International Conference on Nano/Micro Engineered and Molecular Systems (NEMS);2024-05-02

2. In-flight electro-neutralisation electrospray for pulmonary drug delivery;Nano Today;2024-04

3. Charge-Reduced Particles via Self-Propelled Electrohydrodynamic Atomization for Drug Delivery Applications;ACS Applied Materials & Interfaces;2023-06-15

4. Experimental investigation on the spray performance of industrial swirl nozzle assisted by ion wind;Journal of Electrostatics;2023-03

5. Electrohydrodynamic Nebuliser (eNEB) for Direct Pulmonary Drug Delivery Application;2023 IEEE 36th International Conference on Micro Electro Mechanical Systems (MEMS);2023-01-15

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