Prospective Comparison of Tuberculin Skin Test and QuantiFERON-TB Gold In-Tube Assay for the Detection of Latent Tuberculosis Infection among Healthcare Workers in a Low-Incidence Setting-Reference-Cited by-同舟云学术

Prospective Comparison of Tuberculin Skin Test and QuantiFERON-TB Gold In-Tube Assay for the Detection of Latent Tuberculosis Infection among Healthcare Workers in a Low-Incidence Setting

Published:2009-11 Issue:11 Volume:30 Page:1123-1126
ISSN:0899-823X
Container-title:Infection Control & Hospital Epidemiology
language:en
Short-container-title:Infect. Control Hosp. Epidemiol.

Author:

Cummings Kristin J.,Smith Tamara S.,Shogren Elizabeth S.,Khakoo Rashida,Nanda Sharmilarani,Bunner Lana,Smithmyer Ann,Soccorsi Darlene,Kashon Michael L.,Mazurek Gerald H.,Friedman Lloyd N.,Weissman David N.

Abstract

We compared the results of the tuberculin skin test with the results of the QuantiFERON-TB Gold In-Tube (QFT-GIT) assay among 182 low-risk healthcare workers. Overall agreement and specificity were high, but the tests did not agree on positive results. Only 2 of 5 positive QFT-GIT assay results could be confirmed with repeat analyses. Indeterminate results were associated with potential immunosuppression.

Publisher

Cambridge University Press (CUP)

Subject

Infectious Diseases,Microbiology (medical),Epidemiology

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