Loss of LKB1 Kinase Activity in Peutz-Jeghers Syndrome, and Evidence for Allelic and Locus Heterogeneity

Author:

Mehenni Hamid,Gehrig Corinne,Nezu Jun-ichi,Oku Asuka,Shimane Miyuki,Rossier Colette,Guex Nicolas,Blouin Jean-Louis,Scott Hamish S.,Antonarakis Stylianos E.

Publisher

Elsevier BV

Subject

Genetics (clinical),Genetics

Reference32 articles.

1. Fine mapping of a genetic locus for Peutz-Jeghers syndrome on chromosome 19p;Amos;Cancer Res,1997

2. Somatic mutations in LKB1 are rare in sporadic colorectal and testicular tumors;Avizienyte;Cancer Res,1998

3. Low frequency of somatic mutations in the LKB1/Peutz-Jeghers syndrome gene in sporadic breast cancer;Bignell;Cancer Res,1998

4. Knowledge-base prediction of protein structures and the design of novel molecules;Blundell;Nature,1987

5. CHARMM: a program for macromolecular energy, minimization, and dynamics calculations;Brooks;J Comp Chem,1983

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