BRCA1 and BRCA2 Mutation Analysis of 208 Ashkenazi Jewish Women with Ovarian Cancer

Author:

Moslehi Roxana,Chu William,Karlan Beth,Fishman David,Risch Harvey,Fields Abbie,Smotkin David,Ben-David Yehuda,Rosenblatt Jacalyn,Russo Donna,Schwartz Peter,Tung Nadine,Warner Ellen,Rosen Barry,Friedman Jan,Brunet Jean-Sébastien,Narod Steven A.

Publisher

Elsevier BV

Subject

Genetics (clinical),Genetics

Reference35 articles.

1. The founder mutations 185delAG and 5382insC in BRCA1 and 6174delT in BRCA2 appear in 60% of ovarian cancer and 30% of early-onset breast cancer patients among Ashkenazi women;Abeliovich;Am J Hum Genet,1997

2. Genetic epidemiology of epithelial ovarian cancer;Amos;Cancer,1993

3. High frequency of BRCA1 and BRCA2 germline mutations in Ashkenazi Jewish ovarian cancer patients, regardless of family history;Beller;Gynecol Oncol,1997

4. Clinical and pathologic features of hereditary ovarian cancers associated with germline mutations of BRCA1 or BRCA2.;Boyd;Gynecol Oncol,1999

5. Cancer risks in BRCA2 mutation carriers;J Natl Cancer Inst,1999

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