Clinical Experience With Minocycline and Rifampin-Impregnated Central Venous Catheters in Bone Marrow Transplantation Recipients: Efficacy and Low Risk of Developing Staphylococcal Resistance

Author:

Chatzinikolaou Ioannis,Hanna Hend,Graviss Linda,Chaiban Gassan,Perego Cheryl,Arbuckle Rebecca,Champlin Richard,Darouiche Rabih,Samonis George,Raad Issam

Abstract

AbstractIn this retrospective evaluation of the 4-year clinical use of minocycline and rifampin-impregnated catheters in bone marrow transplantation (BMT) patients, we report low risk of development of staphylococcal resistance to the antibiotics coating the catheters and efficacy in preventing primary staphylococcal bloodstream infections.

Publisher

Cambridge University Press (CUP)

Subject

Infectious Diseases,Microbiology (medical),Epidemiology

Reference10 articles.

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4. Hanna H , Benjamin RS , Chatzinikolaou I , et al. The role of long-term silicone central venous catheters impregnated with rifampin and minocycline (S-CVC-RM) in preventing catheter-related infections: a prospective randomized study. Presented at the 38th Annual Meeting of the American Society of Clinical Oncology; May 18-21, 2002; Orlando, FL.

5. In vitro evaluation of the risk of developing bacterial resistance to antiseptics and antibiotics used in medical devices

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