Two-Locus Heterogeneity Cannot Be Distinguished from Two-Locus Epistasis on the Basis of Affected-Sib-Pair Data

Author:

Vieland Veronica J.,Huang Jian

Publisher

Elsevier BV

Subject

Genetics(clinical),Genetics

Reference8 articles.

1. Loci on chromosomes 2 (NIDDM1) and 15 interact to increase susceptibility to diabetes in Mexican Americans;Cox;Nat Genet,1999

2. Inter- and intrafamilial heterogeneity: effective sampling strategies and comparison of analysis methods;Durner;Am J Hum Genet,1992

3. The investigation of linkage between a quantitative trait and a marker locus;Haseman;Behav Genet,1972

4. Some epistatic two-locus models of disease. I. Relative risks and identity-by-descent distributions in affected sib pairs;Hodge;Am J Hum Genet,1981

5. Detecting gene-gene interactions using affected sib pair analysis with covariates;Holmans;Hum Hered,2002

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