Obesity‐Related Pulmonary Arterial Hypertension in Rats Correlates with Increased Circulating Inflammatory Cytokines and Lipids and with Oxidant Damage in the Arterial Wall but not with Hypoxia

Author:

Irwin David C.12,Garat Chrystelle V.13,Crossno Joseph T.13,MacLean Paul S.45,Sullivan Timothy M.1,Erickson Paul F.1,Jackman Matthew R.4,Harral Julie W.1,Reusch Jane E. B.14,Klemm Dwight J.135

Affiliation:

1. Division of Cardiovascular Pulmonary ResearchUniversity of Colorado Anschutz Medical CampusAuroraColoradoUSA

2. Division of CardiologyUniversity of Colorado Anschutz Medical CampusAuroraColoradoUSA

3. Division of Pulmonary Sciences and Critical Care MedicineUniversity of Colorado Anschutz Medical CampusAuroraColoradoUSA

4. Division of EndocrinologyDepartment of MedicineUniversity of Colorado Anschutz Medical CampusAuroraColoradoUSA

5. Colorado Obesity Research InitiativeUniversity of Colorado Anschutz Medical CampusAuroraColoradoUSA

Funder

National Institutes of Health

Publisher

Wiley

Subject

Pulmonary and Respiratory Medicine

Reference67 articles.

1. Centers for Disease Control and Prevention.Overweight and obesity.2010.http://www.cdc.gov/nccdphp/dnpa/obesity/index.htm.

2. National Institute of Diabetes and Digestive and Kidney Diseases Weight‐Control Information Network.Overweight and obesity statistics.http://www.win.niddk.nih.gov/statistics/index.htm.

3. Adiposopathy: why do adiposity and obesity cause metabolic disease?;Bays H;Future Lipidol,2006

4. Obesity: why be concerned?;Brown WV;Am J Med,2009

5. The incidence of co‐morbidities related to obesity and overweight: a systematic review and meta‐analysis;Guh DP;BMC Public Health,2009

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