Hypoxia Preconditioning Increases Survival and Decreases Expression of Toll‐Like Receptor 4 in Pulmonary Artery Endothelial Cells Exposed to Lipopolysaccharide

Author:

Ali Irshad1,Nanchal Rahul12,Husnain Fouad1,Audi Said34,Konduri G. Ganesh25,Densmore John C.5,Medhora Meetha16,Jacobs Elizabeth R.123

Affiliation:

1. Department of MedicineMedical College of WisconsinMilwaukeeWisconsinUSA

2. Milwaukee Initiative in Critical Care Outcomes Research Group (MICCOR)Medical College of WisconsinMilwaukeeWisconsinUSA

3. Clement J. Zablocki Veterans Affairs Medical CenterMilwaukeeWisconsinUSA

4. Department of Biomedical EngineeringMarquette UniversityMilwaukeeWisconsinUSA

5. Department of PediatricsMedical College of WisconsinMilwaukeeWisconsinUSA

6. Department of Radiation OncologyMedical College of WisconsinMilwaukeeWisconsinUSA

Funder

National Heart, Lung, and Blood Institute

Publisher

Wiley

Subject

Pulmonary and Respiratory Medicine

Reference40 articles.

1. Incidence and outcomes of acute lung injury;Rubenfeld GD;N Engl J Med,2005

2. Acute lung injury and the acute respiratory distress syndrome in Ireland: a prospective audit of epidemiology and management;Irish Critical Care Trials Group;Crit Care,2008

3. Animal models of acute lung injury;Matute‐Bello G;Am J Physiol Lung Cell Mol Physiol,2008

4. TLR signaling pathways;Takeda K;Semin Immunol,2004

5. Lipopolysaccharide signaling in endothelial cells;Dauphinee SM;Lab Invest,2006

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