Dynamics of cerebrospinal fluid in correction of degenerative lumbosacral stenozis during the postoperative period in dogs

Author:

Vilkowysky Ilya F.ORCID

Abstract

Dynamics of cerebrospinal fl parameters in postoperative period during correction of degenerative lumbosacral stenosis in dogs is an important diagnostic aspect that allows monitoring changes in the state of animals after surgery. An accurate analysis of cerebrospinal fl id provides a wide range of information about the patients neurological health. The assessment should consist of macroscopic, quantitative and microscopic analyses. Сell count is the most important and potentially sensitive indicator of disease. The aim of this study was to determine changes in the cerebrospinal fluid during the postoperative period in the correction of degenerative lumbosacral stenosis. In the study, there were 9 dogs of various breeds, aged from 2 to 8 years (experimental group), the indicators of cerebrospinal fluid and peripheral blood of 3 healthy outbred dogs obtained as a result of medical examination at the age of up to 5 years were used as a control. Surgical intervention was carried out according to the B.P. Meij, N. Bergknut, which consists in dorsal access to the L7-S 1 vertebral arches, soft tissue dissection, dissection of the dorsal ligament, formation of channels in the cranial articular processes of S 1, L7. From each animal, three liquorograms were taken for examination three times on days 1-3 after surgery, on days 12-15 and 27-30 after surgery. The study of cerebrospinal fluid was performed within 30 minutes after taking. As a result of the data obtained, it was found that the cellular composition of the liquor of dogs in the postoperative period of correction of lumbosacral stenosis was within the physiological norm, erythrocytes in the cerebrospinal fluid were not detected. The number of nucleated cells in operated dogs was the highest on days 1-3 after surgery. On the 12th-15th day after the operation, cytosis in the experimental and control groups of animals was 1.27 cells/l more. On days 27-30 after surgery, cytosis in dogs in the experimental group was lower by 0.45 cells/l compared to the control. Analysis of cerebrospinal fluid can help in the diagnostic assessment of the condition of animals in the postoperative period. However, it should be borne in mind that results are rarely specific to any particular condition and should be interpreted in the light of clinical and additional diagnostic findings.

Publisher

Peoples' Friendship University of Russia

Subject

Materials Science (miscellaneous)

Reference16 articles.

1. Braund KG. Clinical neurology in small animal: localization, diagnosis and treatment. In: Braund, K.G. (ed.). Ithaca, New York: International Veterinary Information Service; 2003.

2. Continual cerebrospinal fluid sampling in the neonatal domestic piglet for biomarker and discovery studies

3. Vatnikov YA, Rotanov DA, Bazhibina EB. Analysis of structure and function of dogs’ erythrocytes with trauma. Veterinary medicine. 2007; (2):44-48. (In Russ.).

4. Vatnikov YA. Immunokorrektsiya reparativnogo osteogeneza u eksperimental’nykh zhivot-nykh [Immunocorrection of reparative osteogenesis in experimental animals]. Moscow: RUDN publ.; 2009. (In Russ.).

5. Vatnikov YA. Characteristics of hematopoiesis in multiple injuries in dogs. Veterinary pathology. 2012; (4):45-48. (In Russ.).

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3