Local hardware hypothermia influence on the physiological processes

Abstract

Relevance. Cold vasodilation is a response to a decrease in local and general temperature. Dose-controlled hypothermia is a therapeutic method for treating various pathological processes. Materials and Methods. In our study, we analyzed various indicators of the general condition of the human body under the influence of local controlled hypothermia. The study involved 25 healthy volunteers from the age of 21 to 34, including 14 males and 11 females. The study was carried out at a constant temperature of 25 ºС, relative humidity of 30 ± 5%, and an atmospheric pressure of 765mm Hg in silence and moderate illumination. The instruments of these indicators were bio-impedancemetry, angioscanning, as well as general thermometry. We also performed local thermometry of the buccal mucosa to identify temperature correlations between local hypothermia and buccal mucosa temperature. Local сontrolled hypothermia of the face was carried out by applying an elastic mask to the subject’s face. The mask had a system of irrigation tubes connected to the «ViTherm» device, which cooled the liquid and maintained its circulation. Due to the circulation of the cooled liquid in the mask the face was cooled. The mask covered the parotid-chewing, buccal, zygomatic, and infraorbital regions on the right and left. LCG lasted 50 minutes, and the circulating fluid temperature was 18 ºС. Results and Discussion. The effect of local controlled hypothermia at 18-20 °C did not affect vital signs in healthy adults: active cell mass, electrical reactance, extracellular fluid, oxygen saturation, the duration of systole. pulse. general temperature. At the same time, a decrease in tissue hydration was recorded. The revealed physiological effect of local hypothermia justifies using this temperature regime to reduce postoperative edema. Conclusion. Due to the absence of negative effects of local controlled hypothermia on the vital signs of the human body, the development and application of this tool in clinical practice, including the dental surgeon. is relevant.