Studies of dose distribution to Lung and Stomach and Estimation of Second Cancer Risk due to Outfeld Dose in Radiotherapy with 60Co Teletherapy Beam

Author:

MZ Hossain,MUH Musfika,N Arobi,T Siddiqua,HM Jamilc,AKM Moinul Haque Meaze,Md Shakilur Rahman

Abstract

A critical component of the radiation regimen for treating cancer patients is the precise dose delivery to the treatment organ while minimizing the dose to the healthy tissue. This study aims to evaluate in-field organ dose and dose distribution outside the target organs to estimate the excess lifetime risk of second cancer. The study was carried out with a male Alderson Rando Phantom. 20 sets of thermoluminescence dosimeters (MTS-100) were used in this study. The in-field organs absorbed dose was measured by inserting TLDs at different geometrical depths of the left lung, right lung, and stomach, and for peripheral organs skin dose TLDs were placed at the surface of the corresponding organs. Target organs were irradiated at 100 cGy and 200 cGy by a 60Co teletherapy unit, and irradiated TLDs were read out by a RE-2000 TLD reader. For precise dose delivery to the cancerous organs by 60Co teletherapy, the depth dose correction factor for lung cancer treatment is 0.8667 ± 0.01, and for the stomach is 0.7856 ± 0.017. In the case of the treatment for the lung and stomach, the closest organs received significant doses compared to the other distant organs. Thus, the risk of second cancer due to the peripheral dose is obtained. The stomach is at the highest risk when the lung is the target and the liver is at the highest risk when the stomach is the targeted organ.

Publisher

Heighten Science Publications Corporation

Subject

General Chemical Engineering

Reference38 articles.

1. 1. Sant' A. Dose distribution in healthy tissues by computer modeling of the Alderson Rando phantom in Monte Carlo method. 2019.

2. 2. Bahreyni Toossi MT, Soleymanifard S, Farhood B, Mohebbi S, Davenport D. Assessment of accuracy of out-of-field dose calculations by TiGRT treatment planning system in radiotherapy. J Cancer Res Ther. 2018 Apr-Jun;14(3):634-639. doi: 10.4103/0973-1482.176423. PMID: 29893331.

3. 3. https://www.who.int/news-room/fact-sheets/detail/cancer

4. 4. Baskar R, Lee KA, Yeo R, Yeoh KW. Cancer and radiation therapy: current advances and future directions. Int J Med Sci. 2012;9(3):193-9. doi: 10.7150/ijms.3635. Epub 2012 Feb 27. PMID: 22408567; PMCID: PMC3298009.

5. 5. International Atomic Energy Agency. TRS-398, Absorbed dose determination in external beam radiotherapy: an international code of practice for dosimetry based on standards of absorbed dose to water. Vienna: IAEA; 2000.

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