The public health and economic burden of long COVID in Australia, 2022–24: a modelling study

Author:

Costantino Valentina1ORCID,Grafton Quentin2,Kompas Tom3,Chu Long2,Honeyman Damian1,Notaras Adriana1,MacIntyre C Raina1

Affiliation:

1. The Kirby Institute Sydney NSW

2. Crawford School of Public Policy Australian National University Canberra ACT

3. Centre of Excellence for Biosecurity Risk Analysis University of Melbourne Melbourne VIC

Abstract

AbstractObjectiveTo estimate the number of people in Australia with long COVID by age group, and the associated medium term productivity and economic losses.Study designModelling study: a susceptible–exposed–infected–recovered (SEIR) model to estimate the number of people with long COVID over time following single infections, and a labour supply model to estimate productivity losses as a proportion of gross domestic product (GDP).SettingAustralia, 2022–2024.Main outcome measuresEstimated number of people infected with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) during 2022–2023 (based on serosurvey data) who have long COVID, 2022–2024, by age group; estimated GDP loss during 2022 caused by reduced labour supply attributable to long COVID.ResultsOur model projected that the number of people with long COVID following a single infection in 2022 would peak in September 2022, when 310 341–1 374 805 people (1.2–5.4% of Australians) would have symptoms of long COVID, declining to 172 530–872 799 people (0.7–3.4%) in December 2024, including 7902–30 002 children aged 0–4 years (0.6–2.2%). The estimated mean labour loss attributable to long COVID in 2022 was projected to be 102.4 million (95% confidence interval [CI], 50.4–162.2 million) worked hours, equivalent to 0.48% (95% CI, 0.24–0.76%) of total worked hours in Australia during the 2020–21 financial year. The estimated mean GDP loss caused by the projected decline in labour supply and reduced use of other production factors was $9.6 billion (95% CI, $4.7–15.2 billion), or 0.5% of GDP. The estimated labour loss was greatest for people aged 30–39 years (27.5 million [95% CI, 16.0–41.0 million] hours; 26.9% of total labour loss) and people aged 40–49 years (24.5 million [95% CI, 12.1–38.7 million] hours; 23.9% of total labour loss).ConclusionWidespread SARS‐CoV‐2 infections in Australia mean that even a small proportion of infected people developing long COVID‐related illness and disability could have important population health and economic effects. A paradigm shift is needed, from a sole focus on the immediate effects of coronavirus disease 2019 (COVID‐19) to preventing and treating COVID‐19 and treating long COVID, with implications for vaccine and antiviral policy and other mitigation of COVID‐19.

Funder

National Health and Medical Research Council

Publisher

Wiley

Reference39 articles.

1. Development of a Definition of Postacute Sequelae of SARS-CoV-2 Infection

2. Centers for Disease Control and Prevention.Long COVID basics. Updated 11 June2024.https://www.cdc.gov/covid/long‐term‐effects/?CDC_AAref_Val=https://www.cdc.gov/coronavirus/2019‐ncov/long‐term‐effects(viewed June 2024).

3. World Health Organization.Post COVID‐19 condition (long COVID). 7 Dec 2022.https://www.who.int/europe/news‐room/fact‐sheets/item/post‐COVID‐19‐condition(viewed Nov 2023).

4. National Institute for Health and Care Excellence.COVID‐19 rapid guideline: managing the long‐term effects of COVID‐19 [NG188]. Updated 25 Jan 2024.https://www.who.int/docs/default‐source/immunization/sage/covid/sage‐prioritization‐roadmap‐covid19‐vaccines.pdf?Status=Temp&sfvrsn=bf227443_2(viewed June 2024).

5. Studying the post-COVID-19 condition: research challenges, strategies, and importance of Core Outcome Set development

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