The Platelet Automesoconcentrate in Patients with Orthopedical Pathology

Abstract

The platelet automesoconcentrate is a complex biotechnological product based on autologous growth factors and oligopeptides obtained from the patient's blood platelets. The purpose of this study was evaluation of our own first treatment results and improvement of the quality of life in patients with pathology of the musculoskeletal system after treatment with platelet automesoconcentrate. Material and methods. We analyzed the results of 76 patients (24 patients with knee osteoarthritis, 21 patients with epicondylitis of the elbow joint and 31 patients with the knee joint meniscal lesions Stoller I-IIb), who were treated in the clinic of the State Institution "Institute of Traumatology and Orthopedics" of Academy of Medical Sciences of Ukraine and in the “Virtus” clinic. The quantitative and qualitative evaluation of pain was performed by visual analog scale score. The evaluation of dysfunction and quality of life were performed by the standardized Lysholm and Oxford scales according to the affected segment and pathology. Results and discussion. The positive dynamics of the knee joint functional ability was observed in cases of the 1 and 2 osteoarthrosis grades by 43.6% and 62.1% (in a year). In patients with osteoarthrosis grade 3, a slight improvement was observed in a short-term period, but after 6 months received results gradually decrease and after a year, they were only 4.3% compared with the baseline level (Oxford). The positive dynamics of the elbow joint functional ability for 3 months was 75%. In general, after 6 months, full recovery of the elbow joint function was observed in 15 patients, restrictions at high physical exertion remained in 6 patients. In case of the knee joint menisci lesion, an increase in functional activity was observed in 23 cases by more than 58.8% (Oxford) and increased mean values from 70 (before treatment) to 82 points (Lysholm). Conclusion. The study showed advantages of the platelets automesoconcentrate in patients with osteoarthrosis and the knee meniscal lesions, elbow joint epicondylitis, in clinically difficult cases with the ineffectiveness of previous treatment