CASE OF PAROXYSMAL NOCTURNAL HEMOGLOBINURIA. PROBLEMS OF LABORATORY DIAGNOSTICS

Author:

Sosnin D. Y.,Shchekotova A. P.,Pavlenina L. S.,Piniagina P. D.

Abstract

The presented case demonstrates the importance of a comprehensive analysis of all the examination data in a patient with paroxysmal nocturnal hemoglobinuria (PNH). A comparison was made of anamnesis data, the clinical picture of the disease, the results of biochemical blood analysis and hematological analyzer data with morphological assessment of cells in a stained blood smear. The interest of this case for hematologists and laboratory specialists is due to the rarity of this disease, difficulties in diagnostics, the presence of 2 types of hemolysis, features of morphological changes in peripheral blood erythrocytes, as well as analysis of the dynamics of manifestations, including against the background of targeted therapy of PNH.

Publisher

Izdatel'skii dom Spektr, LLC

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