Theta Rhythmopathy as a Cause of Cognitive Disability in TLE-Reference-Cited by-同舟云学术

Theta Rhythmopathy as a Cause of Cognitive Disability in TLE

Published:2017-03 Issue:2 Volume:17 Page:107-111
ISSN:1535-7597
Container-title:Epilepsy Currents
language:en
Short-container-title:Epilepsy Curr

Author:

Shuman Tristan¹,Amendolara Benjamin¹²³,Golshani Peyman¹⁴⁵⁶

Affiliation:

1. Departments of Neurology and Psychiatry, David Geffen School of Medicine, University of California Los Angeles (UCLA), Los Angeles, CA

2. Neuroscience Interdepartmental Program, UCLA, Los Angeles, CA

3. UCLA Medical Scientist Training Program, Los Angeles, CA

4. West Los Angeles Veterans Affairs Medical Center, Los Angeles, CA

5. Integrative Center for Learning and Memory, UCLA, Los Angeles, CA

6. Intellectual and Developmental Disability Research Center, UCLA, Los Angeles, CA

Abstract

Memory difficulties are commonly associated with temporal lobe epilepsy (TLE) and cause significant disability. This article reviews the role of altered hippocampal theta oscillations and theta-gamma coupling as potential causes of memory disturbance in temporal lobe epilepsy, dissecting the potential mechanisms underlying these changes in large-scale neuronal synchronization. We discuss development of treatments for cognitive dysfunction directed at restoring theta rhythmicity and future directions for research.

Publisher

SAGE Publications

Subject

Neurology (clinical)

Link

http://journals.sagepub.com/doi/pdf/10.5698/1535-7511.17.2.107

Reference66 articles.

1. COGNITIVE DEFICITS IN TEMPORAL LOBE EPILEPSY

2. Effects of chronic epilepsy on declarative memory systems

3. Chronic epilepsy and cognition: A longitudinal study in temporal lobe epilepsy

4. Long term effects of refractory temporal lobe epilepsy on cognitive abilities: a cross sectional study

5. Cognitive prognosis in chronic temporal lobe epilepsy

Cited by 37 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Disrupted Hippocampal Theta-Gamma Coupling and Spike-Field Coherence Following Experimental Traumatic Brain Injury;2024-05-30

2. EEG band power and phase‐amplitude coupling in patients with Dravet syndrome;Annals of the Child Neurology Society;2024-03-26

3. A biologically inspired repair mechanism for neuronal reconstructions with a focus on human dendrites;PLOS Computational Biology;2024-02-23

4. A biologically inspired repair mechanism for neuronal reconstructions with a focus on human dendrites;2023-06-16

5. Cannabinoid regulation of neurons in the dentate gyrus during epileptogenesis: Role of CB1R‐associated proteins and downstream pathways;Epilepsia;2023-03-20