Determination of Satranidazole through Ion-Associative Complex Reaction-Reference-Cited by-同舟云学术

Determination of Satranidazole through Ion-Associative Complex Reaction

Published:2019-03-30 Issue:1 Volume:4 Page:23-27
ISSN:2456-8937
Container-title:Asian Journal of Organic & Medicinal Chemistry
language:en
Short-container-title:Asian J. Org. Med. Chem.

Author:

Kumar K. Kiran¹,Nadh R. Venkata²,Kishore M. Siva¹,Prasad G. Giri³

Affiliation:

1. Department of Chemistry, K.B.N. College, Vijayawada-520001, India

2. Department of Chemistry, GITAM University-Bengaluru, Bengaluru-562163, India

3. Department of Chemistry, Acharya Nagarjuna University, Nagarjuna Nagar-522510, India

Abstract

A simple, selective, accurate and low-cost spectrophotometric method has been described for determination of satranidazole in bulk and pharmaceutical formulations. The developed method involves the formation of chloroform extractable colored ion-association complex of satranidazole with Tropaeolin OOO (TPooo). The extracted colored complex showed absorbance maximum at wavelength 484 nm and obeying Beer′s law in the concentration 4-20 μg mL-1 with the correlation coeffiecent of 0.9998. The results of statistical analysis of the proposed method reveals high accuracy and good precession. Thus, the proposed method can be used commercially for the determination of satranidazole in bulk and pharmaceutical formulations.

Publisher

Asian Journal of Chemistry

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