Synthesis, Characterization, Crystal and Molecular Structure Analysis of 1-(2-Chlorophenyl)-3-methyl-4-(p-tolylthio)-1H-pyrazol-5-ol-Reference-Cited by-同舟云学术

Synthesis, Characterization, Crystal and Molecular Structure Analysis of 1-(2-Chlorophenyl)-3-methyl-4-(p-tolylthio)-1H-pyrazol-5-ol

Published:2019 Issue:4 Volume:4 Page:267-272
ISSN:2456-8937
Container-title:Asian Journal of Organic & Medicinal Chemistry
language:en
Short-container-title:Asian J. Org. Med. Chem.

Author:

Kamani Ronak D.¹,Thummar Rahul P.¹,Sapariya Nirav H.²,Vaghasiya Beena K.¹,Avalani Jemin R.³,Purohit Vishal B.³,Patel Kirit H.¹,Raval Dipak K.¹

Affiliation:

1. Department of Chemistry, Sardar Patel University, Vallabh Vidyanagar-388120, India

2. Department of Chemistry, Natubhai V. Patel College of Pure and Applied Sciences, Vallabh Vidyanagar- 388120, India

3. Department of Chemistry, Shree A.N. Patel P.G. Institute of Science and Research, Anand-388001, India

Abstract

The synthesis of a novel tolylthiopyrazol bearing methyl group has been achieved by transition metal free N-chlorosuccinimide mediated direct sulfenylation of 1-aryl pyrazolones at room temperature. The product obtained was characterized by spectroscopic techniques and finally confirmed by X-ray diffraction studies. The compound 1-(2-chlorophenyl)-3-methyl-4-(p-tolylthio)-1H-pyrazol-5-ol (m.f. C17H15N2OSCl) crystallizes in monoclinic crystal class in space group P21/c with cell parameters a = 9.6479(5) Å, b = 15.1233(8) Å, c = 11.4852(6) Å, β = 108.374(2)°, V=1590.4(2) Å3 and Z = 4. The final residual factor R1 = 0.0499.

Publisher

Asian Journal of Chemistry

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