Microwave Mediated Michaelis-Arbuzov Reaction to Synthesize Bioactive Phenylphosphonate Derivatives Under Solvent Free Condition-Reference-Cited by-同舟云学术

Microwave Mediated Michaelis-Arbuzov Reaction to Synthesize Bioactive Phenylphosphonate Derivatives Under Solvent Free Condition

Published:2019-03-30 Issue:1 Volume:4 Page:1-6
ISSN:2456-8937
Container-title:Asian Journal of Organic & Medicinal Chemistry
language:en
Short-container-title:Asian J. Org. Med. Chem.

Author:

Sujatha B.¹,Subramanyam Ch.²,Rao K. Prasada²

Affiliation:

1. Department of Chemistry, Y.A. Government Degree College for Women, Chirala-523155, India

2. Department of Chemistry, Bapatla Engineering College, Bapatla- 522101, India

Abstract

Microwave assisted easy, efficient, and environment friendly process has been devised for the synthesis of phosphonates within minutes via microwave-assisted Michaelis-Arbuzov reaction. The desired products were obtained in excellent yields and in high purity under solvent-free and catalyst-free conditions. The structure of all the synthesized compounds was confirmed by spectral and CHN analysis. in vitro Antibacterial and antifungal activity of these compounds was also analyzed. Majority of the title compounds showed good inhibition towards bacteria and fungi.

Publisher

Asian Journal of Chemistry

Reference29 articles.

1. R. Engel, Handbook of Organophosphorus Chemistry, Marcel Dekker: New York (1992).

2. P. Savignac and B. Iorga, Modern Phosphonate Chemistry, CRC Press: Boca Raton: FL (2003).

3. J. Svara, N. Weferling and T. Hofmann, Phosphorus Compounds, Organic, In: Ullmann’s Encyclopedia of Industrial Chemistry, Wiley-VCH: Weinheim (2008).

4. A Novel Class of Herbicides (Specific Inhibitors of Imidazoleglycerol Phosphate Dehydratase)

5. F.B. Abeles, P.W. Morgan and M.E. Saltveit, Ethylene in Plant Biology, Academy Press, Inc.: California, edn 2, Chap. 9 (1992).

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Improvements, Variations and Biomedical Applications of the Michaelis–Arbuzov Reaction;International Journal of Molecular Sciences;2022-03-21

2. Greener approach toward synthesis of biologically active s ‐Triazine ( TCT ) derivatives: A recent update;Journal of Heterocyclic Chemistry;2021-07-19