Affiliation:
1. Pharmacogenomics Laboratory, Department of Biosciences, Barkatullah University, Bhopal-462026, India
Abstract
Nowadays, leukotriene antagonistic agents are playing an important role in the management of asthma,
rhinitis and other inflammatory diseases of the lower respiratory tract. Leukotriene antagonistic agents
available in the market are montelukast, pranulukast, zafirlukast, iralukast, cinalukast, zileuton, verlukst
and so on. However, due to several side effects of above allopathic medicines, the bioactive compounds
of plant origin are playing a very important role as secondary metabolites. These bioactive compounds
are still being used by the human beings since time immemorial in the form of herbal preparations for
the treatment of various ailments as mentioned in Ayurvedic system of medicine (ASM). Many
researches have been reported related to the anti-inflammatory properties of plants in the traditional
medicines, which are capable of suppressing, reducing and relieving pain as well as in reducing
inflammation. Therefore, there is a need to highlights some plant species and their by-products
possessing anti-inflammatory and leukotriene antagonistic properties
Publisher
Asian Journal of Chemistry