Affiliation:
1. School of Science, Department of Chemistry, RK University, Rajkot-360020, India
2. Department of Chemistry, Saurashtra University, Rajkot-360005, India
Abstract
A new series of 4-((5-(2-chlorophenyl)-1,3,4-oxadiazol-2-yl)methoxy)-N-(benzylidene
derivatives)benzenamine (5a-k) have been synthesized and were screened for their in vitro antibacterial
activity against Gram-positive bacteria (Pseudomonas aeruginosa, Streptococcus pyogenes),
Gram-negative bacteria (Escherichia coli, Staphylococcus aureus) and antifungal activity (Candida
albicans, Aspergillus niger, Aspergillus clavatus). Synthesized compounds were characterized by IR,
mass (MS), 1H NMR and 13C NMR spectra. The synthesized compounds 5b, 5c, 5g and 5i showed
potency in terms of antimicrobial activity against tested microorganisms.
Publisher
Asian Journal of Chemistry
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