Affiliation:
1. DCS's Annasaheb Ramesh Ajmera College of Pharmacy, Nagaon-424005, India
Abstract
In this work, we have performed 3D QSAR study of reported pyridone-pyrimidone derivatives. CoMFA
was applied to generate 3D QSAR models. Total eight QSAR models were generated. Model 2 was
close to standard set criteria. Effect of steric and electrostatic substituents on biological activity was
observed on contour maps. This study will be helpful for future researchers in designing new pyridinepyrimidone
derivatives.
Publisher
Asian Journal of Chemistry