Synthesis of Formic Acid Catalyzed and Cyclized Novel Modified Route for N,7-diphenyl-7H-benzo[7,8]chromeno[2,3-d]pyrimidin-8-amine Derivatives and Study of their Antimicrobial Profile

Abstract

A new series of N,7-diphenyl-7H-benzo[7,8]chromeno[2,3-d]pyrimidin-8-amine derivatives was synthesized using formic acid as catalyzed and solvent. The structures of new derivatives were confirmed by the spectral data and elemental analyses. Moreover, antimicrobial and antifungal activities has been carryout using S. aureus, S. pyogenes, E. coli, P. aeruginosa, C. albicans, A. niger and drugs nystatin, greseofulvin, ciprofloxacin, chloramphenicol for all the present compounds.