Efficient Green Synthesis, Molecular Modeling and Antimicrobial Investigations of Novel Chloroflavone Libraries-Reference-Cited by-同舟云学术

Efficient Green Synthesis, Molecular Modeling and Antimicrobial Investigations of Novel Chloroflavone Libraries

Published:2021 Issue:3 Volume:6 Page:161-166
ISSN:2456-8937
Container-title:Asian Journal of Organic & Medicinal Chemistry
language:en
Short-container-title:Asian J. Org. Med. Chem.

Author:

Chobe Santosh S.¹^ORCID,Mali Nilesh J.²^ORCID,Nerkar Charushila K.¹^ORCID,Chobe Savita S.¹^ORCID,Patil Arvind M.³^ORCID,Tated Trupti⁴^ORCID

Affiliation:

1. Organic Research Laboratory, L.V.H. College, Panchvati, Nashik-422003, India

2. Department of Chemistry, M.G.V’s M.S.G. College, Malegaon Camp, Malegaon-423203, India

3. Department of Chemistry, S.N.J.B. Arts, Science and Commerce College, Chandwad-423101, India

4. Sinhgad Institute of Pharmacy, Narhe, Pune-411041, India

Abstract

In this article, a sequence of novel substituted 3-chloroflavones derivatives has been synthesized by using the inexperienced efficiency of solvent polyethylene glycol-400. This novelty of prepared derivatives was examined for their antifungal and their in silco docking study. Polyethylene glycol-400 is known as a green solvent to get to the bottom of the ecosystem’s toxic solvent load. A collection of novel substituted 3-chloroflavones derivatives has been synthesized by using the inexperienced functionality of polyethylene glycol-400 solvent. These newly prepared formulations had been evaluated for their antifungal and their in silico docking study. The structures of all the synthesized compounds were characterized with FT-IR, 1H NMR and HRMS techniques.

Publisher

Asian Journal of Chemistry

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