Synthesis, Spectroscopic, Thermal and in vitro Antimicrobial Activity of Fe(III) and Mn(III) Metal Complexes of Semicarbazone-Reference-Cited by-同舟云学术

Synthesis, Spectroscopic, Thermal and in vitro Antimicrobial Activity of Fe(III) and Mn(III) Metal Complexes of Semicarbazone

Published:2020-02-25 Issue:4 Volume:32 Page:789-794
ISSN:0975-427X
Container-title:Asian Journal of Chemistry
language:en
Short-container-title:Asian J. Chem.

Author:

Somaiya Chintan P.¹,Patel Dinesh S.¹,Jani Darshan H.²

Affiliation:

1. Shree P.M. Patel Institute of Post Graduate Studies and Research in Science (Affiliated to Sardar Patel University, V.V. Nagar), Anand-388001, India

2. Department of Chemistry, Om Science College, Junagadh-362001, India

Abstract

In this work novel pyrazolone based semicarbazone derivatives and their spectroscopic and biological activities were investigated. Pyrazolone based semicarbazone ligands and their Fe(III) and Mn(III) heterochelates were synthesized. The structure of semicarbazone ligands were confirmed by 1H NMR, IR, elemental analysis and their heterochelates were confirmed by thermal studies (TGA/DTG & DSC) and FAB mass spectroscopy. All the ligands and heterochelates were screened for antimicrobial study against Gram positive (Bacillus megaterium, Bacillus subtilis) and Gram negative (E. coli, Klebsiella) microorganisms. The results confirmed that semicarbazone based heterochelates have a great potential and significant for further investigation.

Publisher

Asian Journal of Chemistry

Subject

General Chemistry

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