Affiliation:
1. Department of Pharmacy, Chaitanya Deemed to be University, Hanamakonda-506001, India
Abstract
A series of novel substituted-(E)-2-benzylidene-N-(3-(3-oxo-2,3-dihydro-4H-benzo[b][1,4]oxazin-4-
yl)propyl)hydrazine-1-carbothioamides (9a-j) was synthesized in satisfactory to excellent yield by reacting
(Z)-N′-benzylidene hydrazine carbothioamides (8a-j) with 4-(3-bromo-propyl)-2H-benzo[b][1,4]oxazin-
3(4H)-one (5) in K2CO3 and dry N,N-dimethyl formamide. The novel carbothioamides (9a-j) structures
were confirmed using 1H NMR, IR and mass spectroscopic methods
Publisher
Asian Journal of Chemistry