Antimicrobial and Antioxidant Study of Some Newly Synthesized Chalcones and Cyclohexenone Derivatives

Author:

Sapnakumari M.1ORCID,Divya K.2,Aswin K.B.1,Dalin J.1

Affiliation:

1. Department of Chemistry, St. Agnes Centre for Post Graduate Studies and Research, Mangalore-575002, India

2. Post Graduate Department of Chemistry, B.M.S. College for Women, Autonomous, Basavanagudi, Bengaluru-560004, India

Abstract

Chalcones and cyclohexenone derivatives obtained from various substituted aldehydes and substituted acetophenones are described. Chalcones were obtained by the Claisen-Schmidt condensation reaction of aldehydes with substituted acetophenones. Base catalyzed cyclocondensation of ethyl acetoacetate to chalcones under microwave irradiation leads to the formation of cyclohexenone derivatives. The prepared compounds are characterized by IR, 1H NMR and 13C NMR spectral methods. These are screened for their antimicrobial activity against Staphylococcus aureus, Escherichia coli, Aspergillus niger, Aspergillus flavus and also, for their antioxidant properties.

Publisher

Asian Journal of Chemistry

Subject

General Chemistry

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