Affiliation:
1. Department of Chemistry, S.S.V.P.S’s. L.K. Dr. P.R. Ghogrey Science College, Dhule-424005, India
Abstract
In present work, the carvacrol was derivatized as azo compound by coupling method with eight different
diazonium salts. The newly synthesized azo derivatives of carvacrol screened against four bacterial
species and four fungal species and expressed in terms of zone of inhibition in mm and compared with
standard. Furthermore, enzymatic degradation studies also been done by inoculating these newly
synthesized azo derivatives with Pseudomonas aeruginosa bacterium species, which secretes the
azoreductase enzyme as responsible for reduction of –N=N– linkage into two different primary aromatic
amines, followed by anthelmintic activity and molecular docking study.
Publisher
Asian Journal of Chemistry