Characterization, Molecular Docking, Antimicrobial and Anticancer Studies on 5-Bromo salicylaldehyde-furan-2-yl-methanamine Condensed Schiff Base Rare Earth Metal Complexes-Reference-Cited by-同舟云学术

Characterization, Molecular Docking, Antimicrobial and Anticancer Studies on 5-Bromo salicylaldehyde-furan-2-yl-methanamine Condensed Schiff Base Rare Earth Metal Complexes

Published:2021 Issue:9 Volume:33 Page:2127-2134
ISSN:0975-427X
Container-title:Asian Journal of Chemistry
language:en
Short-container-title:Asian J. Chem.

Author:

Preethi B.¹^ORCID,Jayaprakash R.²^ORCID,Rani S. Kutti¹^ORCID,Vijayakumar N.³^ORCID

Affiliation:

1. Department of Chemistry, B.S. Abdur Rahman Crescent Institute of Science and Technology, Vandalur, Chennai-600048, India

2. Department of Chemistry, School of Arts and Science, Aarupadai Veedu Institute of Technology Campus, Vinayaka Mission’s Research Foundation (Deemed to be University), Chennai-603104, India

3. Department of Biochemistry and Biotechnology, Faculty of Science, Annamalai University, Chidambaram-608002, India

Abstract

This work described the synthesis and characterization of 1-(furan-2-yl) methanamine condensed with 5-bromo-2-hydroxybenzaldehyde Schiff base rare earth metal (Ln3+, Pr3+, Nd3+, Sm3+ and Eu3+) complexes.. They were characterized using relevant spectral techniques and docked against microbial target proteins (1H9Z, 3ZBO) theoretically. The experimental antibacterial and anticancer activities (HeLa, MCF7) of these metal complexes were investigated for biological efficacy. Out of five metal complexes, Pr3+ complex exposed good biological efficacy result in both assays.

Publisher

Asian Journal of Chemistry

Subject

General Chemistry

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