Chemical Constituents of Suaeda monoica and its Biological Activity

Abstract

The ethanolic extract of the aerial parts of Suaeda monoica was successively fractionated using petroleum ether, dichloromethane, ethyl acetate and methanol. The GC-MS analysis of dichloromethane fraction has resulted in the identification of 24 non-polar compounds. N,N-dimethyl-1-dodecanamine (19.13%), methyl (Z)-9-oleate (18.1%) and 2-methoxy-3-(2-propenyl)phenol (12.14%) were the major components and fatty acids methyl esters represented the major class of this nonpolar components. Phytochemical study of the ethyl acetate and methanol fractions led to isolation and identification of seven known compounds identified as pyrogallol, ferulic acid, luteolin, (+)-catechien, gallic acid, naringin and naringenin. Dichloromethane, ethyl aetate and methanol fractions exhibited weak to moderate antioxidant activity using DPPH free radical scavenging method. Ethyl acetate and methanol fractions showed no antifungal activity and weak to good antibacterial activity by diffusion agar technique, while the dichloromethane showed potent activity against all the tested strains. Different fractions revealed weak lipase inhibitory effect.