Synthesis and Cytotoxic Studies of Pyrrolopyrimidine Derivatives-Reference-Cited by-同舟云学术

Synthesis and Cytotoxic Studies of Pyrrolopyrimidine Derivatives

Published:2021 Issue:8 Volume:33 Page:1855-1860
ISSN:0975-427X
Container-title:Asian Journal of Chemistry
language:en
Short-container-title:Asian J. Chem.

Author:

Roopashree Rangaswamy¹^ORCID,Swaroop Toreshettahally R.²^ORCID,Shivaprasad Chalya M.³^ORCID,Jagadish Swamy⁴^ORCID,Rangappa Kanchugarakoppal S.⁵^ORCID

Affiliation:

1. Department of Chemistry, Jain Deemed to be University, Bengaluru-560069, India

2. DOS in Organic Chemistry, University of Mysore, Mysuru-570006, India

3. Department of Chemistry, Government First Grade College for Women, Vijayanagara, Mysuru-570032, India

4. DOS in Chemistry, University of Mysore, Mysuru-570006, India

5. Institution of Excellence, University of Mysore, Mysuru-570006, India

Abstract

The synthesis and in vitro cytotoxicity of new pyrrolopyrimidine derivatives is reported in this work. All the compounds were characterized by IR, NMR and MS. They are examined for cytotoxic activity against HeLa. Pyrrolopyrimidine derivatives of benzyl amine (8g) and 4-bromoaniline (8k) showed a potent activity, which is comparable to that of standard Sorafenib.

Publisher

Asian Journal of Chemistry

Subject

General Chemistry

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