Affiliation:
1. P.G. & Research Department of Chemistry, Government Arts College (Affiliated to Bharathidasan University, Tiruchirappalli), Ariyalur-621713, India
Abstract
The reaction of Cu(NO3)2·3H2O and Ni(NO3)2·6H2O with
E-N-(4-isopropylbenzylidine)isonicotinohydrazide derived from isonicotinic acid hydrazide with
4-isopropyl benzaldehyde were synthesized and characterized structurally by physico-chemical and
spectral techniques. The metal-ligand ratio in metal complexes is in the order of metal:ligand1:ligand2
(1:1:1) indicating the formulae of the complexes as [M(SB)2(NO2)2] (where M = Cu2+ & Ni2+, SB =
C16H17N3O). The magnetic moment and electronic spectral data suggest tetragonal geometry for Cu(II)
complex and octahedral geometry for Ni(II) complex around the central metal ions. The FT-IR and
Far-IR spectroscopic data suggest the bidentate nature of ligand. The geometry of the Cu(II) complex
and its covalence is confirmed by EPR spectral data. The Thermal decomposition of metal complexes
has been identified using thermogravimetric analysis. The conductometric measurements proved the
non-electrolytic behaviour of all the compounds. With the help of the agarose gel electrophoresis
method, the DNA cleavage studies of Schiff base metal complexes were predicted. Also, the in-vitro
antioxidant activity of Cu(II) complex was determined by a free radical scavenging assay.
Publisher
Asian Journal of Chemistry