Affiliation:
1. Department of Chemistry, Institute of Basic Sciences, Dr. Bhimrao Ambedkar University, Khandari Campus, Agra-282002, India
Abstract
Two new series of metal complexes, [M(C18H16N4O4)·2H2O] (CH3COO−)2 and [M(C22H24N4)·2H2O](CH3COO−)2, where M= Co2+/Ni2+/ Cu2+ have been prepared under microwave irradiation condition using microwave synthesizer. All the synthesized compounds were characterized by melting point determination of recrystallized samples, running single spot on TLC, elemental analyses, IR, UV-visible spectral studies. Synthesized macrocyclic complexes have been tested for their antibacterial activity
against two bacteria Klebsiella pneumoniae and Escherichia coli by adopting disk diffusion method. The antibacterial activity was compared with amikacin antibiotic and it has been found that the complexes exhibited potential antibacterial activity. From the antibacterial studies, it has been found that the copper complexes were more effective on the microorganism in comparison to Ni(II) and Co(II) complexes.
Publisher
Asian Journal of Chemistry
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