Assessment of Murraya koenigii Leaf Extract against New Multiple Drug Resistance Human Enteric Pathogens

Abstract

Sewage waters are the primary habitats to harbour antibiotic resistance bacteria (ARB) especially multi-drug resistance (MDR) human enteric pathogens. Microorganisms acquire resistance towards many commercial antibiotics due to their inappropriate use. In this study, human enteric pathogens were isolated, identified and characterized and shows the resistance against five different clinically significant commonly prescribed antibiotics. The bacterial strains were isolated from different sewage treatment plants located in Delhi city, India. Samples were analyzed for the detection of pathogenic human enteric bacteria through morphological, biochemical and molecular analysis. Methanolic leaf extract of Murraya koenigii showed the significant antibacterial activity against multi drug resistant human enteric pathogens. Thus, Murraya koenigii leaves would be a potential alterantive to antibiotic regimens for the prevention of gastrointestinal infections.