Synthesis, Characterization of Metal Complexes of Schiff Base derived from Pyrrole-2-carbaldehyde and 4-Methoxy Aniline and their Biological Studies

Author:

Charles A.1,Krishnaveni R.2ORCID,Sivara K.3

Affiliation:

1. Research and Development Centre, Bharathiar University, Coimbatore-641046, India

2. Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences, Thandalam-602105, India

3. Department of Chemistry, Tamilavel Umamahesuwaranar Karanthai Arts College, Thanjavur-613002, India

Abstract

The metal complexes of Fe(II), Co(II) and Ni(II) have been synthesized from N-((1H-pyrrol-2- yl)methylene)-4-methoxyaniline. The synthesized Schiff base and its metal complexes were structurally characterized based on IR, NMR, UV-vis spectroscopic techniques. The presence of coordinated water molecules were confirmed by thermal studies. All the synthesized compounds were screened for their antibacterial (Escherichia coli, Bacillus substilis, Salmonella typhi, Staphylococcus epidermis) and antifungal (Aspergillus flavus) and DNA cleavage activity.

Publisher

Asian Journal of Chemistry

Subject

General Chemistry

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