A Review of Gene Sequencing in Infertility
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Published:2020-09-30
Issue:3
Volume:68
Page:97-105
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ISSN:0015-5497
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Container-title:Folia Biologica
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language:en
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Short-container-title:folia biol (krakow)
Author:
Zhao Jie,Sha Ri-Na,Liu Fang,Du Chen,Dai Bai,Zhang Yan-Bing,Tian Ru-Gang,He Jiang-Feng,Chen Xiu-Juan
Abstract
Assisted reproductive technology (ART) is the technology used primarily for infertility treatments in order to achieve pregnancy. With the increasing demands of preimplantation genetic testing (PGT), the safety inspection of in-vitro fertilization (IVF), the prevention of pathogenesis
in sterility, the application of gene sequencing technology in ART, and the diagnosis of infertility-related diseases have significantly increased. The development and principles of gene sequencing technology, the application of gene sequencing in PGT, the application of whole genome sequencing
in ART-conceived children, and the application of whole genome sequencing in infertility-related disorders have been summarized in this review.
Publisher
Institute of Systematics and Evolution of Animals, Polish Academy of Sciences
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine