Author:
Н. М. Рзаева ,А. И. Дмитренко ,А. Н. Нуруллаева ,Э. Н. Панахова ,М. Х. Ализаде
Abstract
Researching some aspects of functioning retina performance in conditions of pigmentary dystrophy (PD) will allow revealing a number of features regarding its existence and sequence of restoration both as respector and neural systems.Research objecture. To investigate dynamics of formation of electroretinogram (ERG) in conditions of retina PD. Materials and methods. Chronic experiments were conducted on awake rabbits for a month in the norm and condition of PD. Results. The received results testily that formation a – and b – ERG components in condition of PD was ambiguous. Amplitudes of a – waves higher (76,4%) than those of b – waves (44,4%). Conclusion. Partial recovery of ERG components is a result of the inclusion of retina backup mechanisms capable of withstanding pathological process and restoring vision.
Reference17 articles.
1. Asakava K., Ishikawa H., Uga S. and etc,. Histopathological Changes of İnner Retina. Optic Disc and optic Nerve in Rabbit üith Advanced Retinis Pigmentosa. Neuroophthalmology 2016; 40 (6): 296-291
2. Hirota R., Kondo M., Ueno S., Sakai T., Koyasu T., Terasaki H., Photoreceptor and post-photoreceptoral contributions to photopic ERG a-wave in rhodopsin P347L transgenic rabbits. Invest. Ophthalmol. Vis.Sci.2012: 53(3) P.1467-72
3. Cytoprotective Effects of a NoveiNrt2 Activator, RS9, in Rhadopsin Pro 347 Leu Rabbits. 2016, 41(8): 1123-1126
4. Noell W.K. The effect of iodeacetate on the vertebrate retina. //J.Cell Comp.Physiol. 1951; 37: 1: 288-307. doi.org/10.1002/jcp.1030370209
5. Мирюсифова Х.М., Мамедов З.Г. Сравнительный анализ влияния электрической стимуляции различных структур головного мозга на восстановление наружных слоев сетчатки в условиях ретинальной дистрофии.//М., Журн. Естественные итехнические науки.2013.No4,т.66.с.108-112.