Alcohol consumption and employment: a cross-sectional study of office workers and unemployed people

Author:

De Sio Simone1,Tittarelli Roberta2,Di Martino Giuseppe3,Buomprisco Giuseppe1,Perri Roberto1,Bruno Guglielmo1,Pantano Flaminia4,Mannocchi Giulio5,Marinelli Enrico4,Cedrone Fabrizio3

Affiliation:

1. School of Occupational Medicine—U.R. Occupational Medicine, “Sapienza” University of Rome, Rome, Italy

2. Unit of Forensic Toxicology, Department of Anatomical, Histological, Forensic and Orthopedic Sciences, “Sapienza” University of Rome, Rome, Italy

3. School of Hygiene and Preventive Medicine, University “G.d’Annunzio” of Chieti-Pescara, Chieti, Italy

4. Unit of Forensic Toxicology—Department of Anatomical, Histological, Forensic and Orthopedic Sciences, “Sapienza” University of Rome, Rome, Italy

5. Bioethics and Legal Medicine Centre, School of Law, University of Camerino, Camerino, Italy

Abstract

Background Alcohol is a psychoactive substance with toxic and addictive properties. Biomarkers like GGT, AST, ALT and MCV are influenced by excessive ethanol consumption. Alcohol consumption represents a health risk and it has been linked to unemployment. The aim of this study how working status predict alcohol consumption through a cross sectional study comparing alcohol-related biomarkers levels in office workers and unemployed people. Methods This study includes 157 office workers and 157 unemployed people, who were recruited from January to December 2018. A propensity score matching procedure was applied to obtain two homogenous groups in terms of age and gender. A non-parametric analysis was performed on serum biomarkers that are generally altered by alcohol consumption. Logistic regression models were designed to evaluate how working status predict abnormal biomarker levels related with alcohol consumption. Results No differences in median biomarker values were found between groups. Logistic regression analysis showed that office work is a negative predictor of pathological biomarker levels. Office workers had a significant relation with the levels of GGT (OR 0.48; 95% CI [0.28–0.84]), AST (OR 0.42; 95% CI [0.22–0.78]), ALT (OR 0.39; 95% CI [0.23–0.66]), and MCV (OR 0.37; 95% CI [0.19–0.70]). Conclusion Office workers had lower absolute frequencies of pathological values of alcohol consumption biomarkers, after matching for age and gender compared with unemployed people. In addition, a significant negative association between office work is a negative predictor of biomarker levels of alcohol consumption. These results showed that work is an important determinant of health and that can represent a benefit for workers in terms of reducing the risk of consuming alcohol.

Publisher

PeerJ

Subject

General Agricultural and Biological Sciences,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience

Reference57 articles.

1. Biomarkers of liver status in heavy drinkers, moderate drinkers and abstainers;Alatalo;Alcohol,2009

2. Prevention interventions of alcohol problems in the workplace: a review and guiding framework;Ames;Alcohol Research & Health,2011

3. Alcohol biomarkers in clinical and forensic contexts;Andresen-Streichert;Deutsches Ärzteblatt International,2018

4. Biomarkers of alcohol consumption in patients classified according to the degree of liver disease severity;Anttila;Scandinavian Journal of Clinical and Laboratory Investigation,2005

5. Carbohydrate-deficient transferrin as a marker of chronic alcohol abuse: a critical review of pre-analysis, analysis, and interpretation;Arndt;Clinical Chemistry,2001

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