1. Intensive Care Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom
2. School of Medicine, Dentistry and Biomedical Sciences, The Queen’s University Belfast, Belfast, United Kingdom
3. Faculty of Medicine, Department of Surgery & Cancer, Section of Anaesthetics, Pain Medicine and Intensive Care, Imperial College London, London, United Kingdom
4. Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, United Kingdom