Differential roles of prostaglandin E-type receptors in activation of hypoxia-inducible factor 1 by prostaglandin E1in vascular-derived cells under non-hypoxic conditions

Author:

Suzuki Kengo12,Nishi Kenichiro3,Takabuchi Satoshi3,Kai Shinichi1,Matsuyama Tomonori1,Kurosawa Shin2,Adachi Takehiko4,Maruyama Takayuki5,Fukuda Kazuhiko1,Hirota Kiichi3

Affiliation:

1. Department of Anesthesia, Kyoto University Hospital, Kyoto, Japan

2. Department of Anesthesiology, Tohoku University Hospital, Sendai, Japan

3. Department of Anesthesiology, Kansai Medical University, Hirakata, Osaka, Japan

4. Department of Anesthesia, Tazuke Kofukai Medical Research Institute Kitano Hospital, Osaka, Japan

5. Minase Research Institutes, Research Headquarters, Ono Pharmaceutical, Osaka, Japan

Publisher

PeerJ

Subject

General Agricultural and Biological Sciences,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience

Reference36 articles.

1. Host prostaglandin E(2)-EP3 signaling regulates tumor-associated angiogenesis and tumor growth;Amano;Journal of Experimental Medicine,2003

2. Study of rat hepatocytes in primary culture submitted to hypoxia and reoxygenation: action of the cytoprotectors prostaglandin E1, superoxide dismutase, allopurinol and verapamil;Andrade;Arquivos de Gastroenterologia,2009

3. Alprostadil suppresses angiogenesis in vitro and in vivo in the murine Matrigel plug assay;Cattaneo;British Journal of Pharmacology,2003

4. Dose proportional pharmacokinetics of alprostadil (prostaglandin E1) in healthy volunteers following intravenous infusion;Cawello;British Journal of Clinical Pharmacology,1995

5. International Union of Pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes;Coleman;Pharmacological Reviews,1994

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