Health status risk factors and quality of life in 75–84-year-old individuals assessed for dementia using the short 10/66 dementia diagnostic schedule

Author:

Davis Gershwin1,Baboolal Nelleen2,Tripathi Vrijesh3,Stewart Robert45

Affiliation:

1. Department of Paraclinical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, St. Augustine Campus, Trinidad, Trinidad and Tobago

2. Department of Clinical Medical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad, Trinidad and Tobago

3. Department of Mathematics and Statistics, Faculty of Science and Technology, The University of the West Indies, St. Augustine, Trinidad, Trinidad and Tobago

4. Institute of Psychiatry, Psychology and Neuroscience, King’s College London,, London, United Kingdom

5. South London and Maudsley NHS Foundation Trust, London, United Kingdom

Abstract

Background Trinidad is an island that not only has a population at high vascular risk but also one that is in epidemiological transition with high dementia prevalence. The aim of the study was to investigate modifiable risk factors associated with dementia in middle-old (75–84 years) individuals. Methods As part of a large national community survey of dementia prevalence in Trinidad, 811 people aged 75–84 years were evaluated for dementia using the 10/66 short algorithm. Demographic data collected included information on age, gender, ethnicity, religion, education, occupation, living accommodation, smoking, alcohol consumption, self-reported medical conditions, impairments and ability to do instrumental activities of daily living (IADL). Data were analysed using multivariable logistic regression models. Results Of the 811 participants, nearly 55% were female. The mean age was 78.8 (SD = 2.8) years and dementia was present in 198 (24.4%). Having less than ten years of education, being an agricultural worker, skilled labourer or housewife and having more than four co-morbidities were significantly associated with dementia. The odds ratio for dementia for those having self-reported stroke was 4.93 (95% CI [2.64–9.23]) and for diabetes was 1.76 (95% CI [1.17–2.65]) adjusting for age, age2, gender, ethnicity, religion, education and occupation. Impairment in eyesight, hearing, climbing stairs, and walking were also more common in the group with dementia. Ability to perform IADLs was linked with dementia. Individuals with dementia were more likely to be unable to perform any of the eight IADLs. Those who did not exercise at all (OR 6.95, 95% CI [2.02–23.90]) and those who did low exercise (OR 1.83, 95% CI [1.07–3.13]) compared to those who did moderate to high exercise were also more likely to have dementia. Conclusion In the middle-old population in Trinidad having diabetes and stroke, low IADL score, and no exercise were more common in people with dementia.

Funder

UWI-Trinidad and Tobago Research Development and Impact Fund

Ministry of Health of the Republic of Trinidad and Tobago

Janssen, GSK, Takeda, the National Institute for Health Research

Biomedical Research Centre at South London

Maudsley NHS Foundation Trust and King’s College London

Publisher

PeerJ

Subject

General Agricultural and Biological Sciences,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience

Reference44 articles.

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3. Ascertaining late-life depressive symptoms in Europe: an evaluation of the survey version of the EURO-D scale in 10 nations. The SHARE project;Castro-Costa;International Journal of Methods in Psychiatric Research,2008

4. Prevalence of self –reported diabetes, hypertension and heart disease in individuals seeking State funding in Trinidad and Tobago;Chadee;Journal of Epidemiology and Global Health,2013

5. Racial and ethnic differences in trends in dementia prevalence and risk factors in the United States;Chen;Alzheimer’S & Dementia: Translational Research & Clinical Interventions,2018

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