The syndemic condition of psychosocial problems related to depression among sexually transmitted infections patients

Author:

Xu Chen12,Shi Yuan3,Yu Xiaoyue2,Chang Ruijie2,Wang Huwen2,Chen Hui2,Wang Rongxi2,Liu Yujie2,Liu Shangbin2,Cai Yong2,Ni Yang1,Wang Suping2

Affiliation:

1. Shanghai Skin Disease Hospital, Shanghai, China

2. School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China

3. Shanghai Jiao Tong University School of Medicine, Shanghai, China

Abstract

Background The prevalence of depression in sexually transmitted infections (STIs) patients is much higher than general public. However, studies focusing on comprehensive psychosocial effects on depression among STIs patients are limited. This study aimed to examine association of multiple psychosocial syndemic conditions with depression among STIs patients in Shanghai, China. Methods We conducted a cross-sectional study and recruited 910 STIs patients from Shanghai Skin Disease Hospital. Participants self-reported their demographics and themselves completed the scales of depression, self-esteem, loneliness, social support, entrapment, defeat and interpersonal needs. Logistic regressions were performed to detect the possible contributing psychosocial factors for depression and to verify the syndemic conditions of psychosocial problems. Results Of the STIs patient sample, the prevalence of depression was 17.9%. Multivariable analysis showed low-level self-esteem (odds ratio [ORm]: 2.18, 95% CI [1.19–4.00]) and social support (ORm: 2.18, 95% CI [1.37–3.46]), high-level entrapment (ORm: 6.31, 95% CI [3.75–10.62]) and defeat (ORm: 2.60, 95% CI [1.51–4.48]) increased the risk of depression. Psychosocial syndemic conditions magnified effect in fusing depression (adjusted odds ratio [AOR]: 11.94, 95% CI [7.70–18.53]). Participants with more than 4 psychosocial problems were about 22 times more likely to have depression (AOR: 22.12, 95% CI [13.19–37.09]). Conclusions The psychosocial problems syndemic magnifying the risk of depression was confirmed and psychosocial interventions to prevent depression is needed among STIs patients.

Funder

National Key R&D Program of China

Shanghai Three-year Action Plan for Public Health

Strategic collaborative Innovation Team

Publisher

PeerJ

Subject

General Agricultural and Biological Sciences,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience

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