Population structure ofNeisseria gonorrhoeaebased on whole genome data and its relationship with antibiotic resistance

Author:

Ezewudo Matthew N.1,Joseph Sandeep J.1,Castillo-Ramirez Santiago2,Dean Deborah34,del Rio Carlos15,Didelot Xavier6,Dillon Jo-Anne7,Selden Richard F.8,Shafer William M.910,Turingan Rosemary S.8,Unemo Magnus11,Read Timothy D.1

Affiliation:

1. Department of Medicine, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USA

2. Programa de Genómica Evolutiva, Centro de Ciencias Genómicas, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México

3. Children’s Hospital Oakland Research Institute, Oakland, CA, USA

4. University of San Francisco at California, Division of Infectious Diseases, San Francisco, CA, USA

5. Hubert Department of Global Health, Rollins School of Public Health of Emory University, Atlanta, GA, USA

6. Department of Infectious Disease Epidemiology, Imperial College London, London, UK

7. Department of Microbiology and Immunology, College of Medicine, Vaccine and Infectious Disease Organization International Vaccine Centre, University of Saskatchewan, Saskatoon, Saskatchewan, Canada

8. NetBio, Waltham, MA, USA

9. Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA

10. Laboratories of Bacterial Pathogenesis, Veterans Affairs Medical Center, Decatur, GA, USA

11. WHO Collaborating Centre for Gonorrhoea and other STIs, Örebro University Hospital, Örebro, Sweden

Publisher

PeerJ

Subject

General Agricultural and Biological Sciences,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience

Reference55 articles.

1. Mosaic-like structure of penicillin-binding protein 2 Gene (penA) in clinical isolates of Neisseria gonorrhoeae with reduced susceptibility to cefixime;Ameyama;Antimicrobial Agents and Chemotherapy,2002

2. Controlling the false discovery rate: a practical and powerful approach to multiple testing;Benjamini;Journal of the Royal Statistical Society Series B,1995

3. Phylogeographic variation in recombination rates within a global clone of methicillin-resistant Staphylococcus aureus;Castillo-Ramírez;Genome Biology,2012

4. Emergence of high-level azithromycin resistance in Neisseria gonorrhoeae in England and Wales;Chisholm;The Journal of Antimicrobial Chemotherapy,2009

5. Bayesian identification of admixture events using multilocus molecular markers;Corander;Molecular Ecology,2006

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