Modeling functional changes toEscherichia colithymidylate synthase upon single residue replacements: a structure-based approach
Author:
Affiliation:
1. Laboratory for Structural Bioinformatics, School of Systems Biology, George Mason University, Manassas, VI, USA
Publisher
PeerJ
Subject
General Agricultural and Biological Sciences,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience
Link
https://peerj.com/articles/721.pdf
Reference43 articles.
1. The quickhull algorithm for convex hulls;Barber;ACM Transactions on Mathematical Software,1996
2. The protein data bank;Berman;Nucleic Acids Research,2000
3. A method to identify protein sequences that fold into a known three-dimensional structure;Bowie;Science,1991
4. Random forests;Breiman;Machine Learning,2001
5. SNAP: predict effect of non-synonymous polymorphisms on function;Bromberg;Nucleic Acids Research,2007
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