The relationship between sleep duration and activities of daily living (ADL) disability in the Chinese oldest-old: A cross-sectional study

Author:

Wang Zhaoping1,Ni Xiaolin1,Gao Danni12,Fang Sihang1,Huang Xiuqing1,Jiang Mingjun3,Zhou Qi1,Sun Liang1,Zhu Xiaoquan1,Su Huabin4,Li Rongqiao4,Huang Bin4,Lv Yuan4,Pang Guofang4,Hu Caiyou4,Yang Ze1,Yuan Huiping12

Affiliation:

1. The Key Laboratory of Geriatrics, Beijing Institute of Geriatrics, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing Hospital/National Center of Gerontology of National Health Commission, Beijing, China

2. Peking University Fifth School of Clinical Medicine (Beijing Hospital), Beijing, China

3. Respiratory Department, Beijing Children’s Hospital, Capital Medical University, China National Clinical Research Center of Respiratory Diseases, National Center for Children’s Health, Beijing, China

4. Jiangbin Hospital, Guangxi Zhuang Autonomous Region, Nanning, Guangxi, China

Abstract

Objective To investigate the relationship between sleep duration and activities of daily living (ADL) disability, and to explore the optimal sleep duration among oldest-old Chinese individuals. Methods In this cross-sectional study, 1,798 participants (73.2% female) were recruited from Dongxing and Shanglin in Guangxi Zhuang Autonomous Region, China in 2019. The restricted cubic spline function was used to assess the dose-response relationship between sleep duration and ADL disability, and the odds ratios (ORs) of the associations were estimated by logistic regression models. Results The overall prevalence of ADL disability was 63% (64% in females and 58% in males). The prevalence was 71% in the Han population (72% in females and 68% in males), 60% in the Zhuang population (62% in females and 54% in males) and 53% in other ethnic population (53% in females and 53% in males). A nonlinear relationship between sleep duration and ADL disability was observed. Sleep duration of 8-10 hours was associated with the lowest risk of ADL disability. Sleep duration (≥12 hours) was associated with the risk of ADL disability among the oldest-old individuals after adjusting for confounding factors (OR = 1.47, 95% CI [1.02, 2.10], p < 0.05). Conclusion Sleep duration more than 12 hours may be associated with an increased risk of ADL disability in the oldest-old individuals, and the optimal sleep duration among this population could be 8–10 h.

Funder

National Key R&D Program of China

Natural Science Foundation of China

Beijing Hospital Doctoral Scientific Research Foundation

Beijing Hospital Nova Project

Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences

CAMS Innovation Fund for Medical Sciences

Priority Union Foundation of Yunnan Provincial Science and Technology Department and Kunming Medical University

Publisher

PeerJ

Subject

General Agricultural and Biological Sciences,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience

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