ClusterEnG: an interactive educational web resource for clustering and visualizing high-dimensional data

Author:

Manjunath Mohith1,Zhang Yi12,Kim Yeonsung1,Yeo Steve H.1,Sobh Omar1,Russell Nathan3,Followell Christian3,Bushell Colleen3,Ravaioli Umberto4,Song Jun S.15

Affiliation:

1. Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Champaign, IL, United States of America

2. Department of Bioengineering, University of Illinois at Urbana-Champaign, Champaign, IL, United States of America

3. Illinois Applied Research Institute, University of Illinois at Urbana-Champaign, Champaign, IL, United States of America

4. Department of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, Champaign, IL, United States of America

5. Department of Physics, University of Illinois at Urbana-Champaign, Champaign, IL, United States of America

Abstract

Background Clustering is one of the most common techniques in data analysis and seeks to group together data points that are similar in some measure. Although there are many computer programs available for performing clustering, a single web resource that provides several state-of-the-art clustering methods, interactive visualizations and evaluation of clustering results is lacking. Methods ClusterEnG (acronym for Clustering Engine for Genomics) provides a web interface for clustering data and interactive visualizations including 3D views, data selection and zoom features. Eighteen clustering validation measures are also presented to aid the user in selecting a suitable algorithm for their dataset. ClusterEnG also aims at educating the user about the similarities and differences between various clustering algorithms and provides tutorials that demonstrate potential pitfalls of each algorithm. Conclusions The web resource will be particularly useful to scientists who are not conversant with computing but want to understand the structure of their data in an intuitive manner. The validation measures facilitate the process of choosing a suitable clustering algorithm among the available options. ClusterEnG is part of a bigger project called KnowEnG (Knowledge Engine for Genomics) and is available at http://education.knoweng.org/clustereng.

Funder

National Institute of General Medical Sciences (NIGMS)

Publisher

PeerJ

Subject

General Computer Science

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