A Description on the Shake-Flask and Laser Monitoring-Based Techniques for Determination of the Drug’s Solubility

Author:

Zarghampour Aynaz1ORCID,Jouyban Kimiya2,Jouyban-Gharamaleki Vahid34,Jouyban Abolghasem15,Rahimpour Elaheh16ORCID

Affiliation:

1. Pharmaceutical Analysis Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.

2. Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran.

3. Kimia Idea Pardaz Azarbayjan (KIPA) Science Based Company, Tabriz University of Medical Sciences, Tabriz, Iran.

4. Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

5. Faculty of Pharmacy, Near East University, PO BOX: 99138 Nicosia, North Cyprus, Mersin 10, Turkey.

6. Infectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Abstract

In the current work, the performance of the shake-flask and laser monitoring-based techniques for the determination of the solubility is described as a video file. The video is prepared in three parts. The first part is a general explanation of solubility and its manual and automatic measurement methods. The second part is about how to perform the shake-flask method to measure drug solubility, and the third part is about how the laser monitoring -based automatic device works to measure drug solubility.

Publisher

Maad Rayan Publishing Company

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