Anti-N-methyl D-aspartate Receptor Encephalitis Following ChAdOx1 nCoV-19 Vaccination: A Case Report

Author:

Liyaghatdar Zahra1ORCID,Rahimkhani Amirhosein2,Liaghatdar Amin2ORCID

Affiliation:

1. Department of Biochemistry, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran

2. Faculty of Medical Sciences, Zahedan University of Medical Sciences, Zahedan, Iran

Abstract

As of December 2020, millions of people have been immunized using vaccines against SARS-CoV-2. A wide range of neurological adverse effects of SARS-CoV-2 vaccines have been reported so far. Here, we report a 23-year-old male who experienced psychiatric symptoms, loss of consciousness, language disintegration, and incontinency that happened 10 days after the first dosage of the COVID-19 AstraZeneca vaccine. Anti-NMDAR Encephalitis was diagnosed based on the results of the autoimmune panel. The patient responded to intravenous dexamethasone very well and experienced no other complications in 6 months of follow-up. Scientific reports of neurological side effects such as anti-NMDAR encephalitis after vaccination are necessary to optimize the safety and effectiveness of SARS-CoV-2 vaccines.

Publisher

Maad Rayan Publishing Company

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. AZD-1222/Methylprednisolone/Prednisolone;Reactions Weekly;2024-03-02

2. Immune-mediated encephalitis following SARS-CoV-2 vaccinations;Clinical Neurology and Neurosurgery;2024-03

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